 Botanical
Herbal Formula (BH-5) for Aplastic Anemia (AA)
Researchers:
Ba X, Hoang MD, PhD
Greame Shaw MD
Abstract: We have identified 5 herbs and created
a specific formula ratio and concentration that has
been shown to have great success in helping people with
Aplastic Anemia.
In
order to evaluate the efficacy and safety of botanical
herbs in people with Alpastic Anemia, we used a specific
compound (BH-5) of 5 herbs in a special formulation
and concentration. A group of 19 people with biopsy
proven AA were enrolled in this prospective trial between
February 1994 and December 2000. A minimum follow-up
of 12 months was required. All 19 people were evaluated.
Age ranged from 6-67 years old. The disease was confirmed
by bone marrow aspiration and trephine biopsy. Physical
examination and routine investigations were carried
out monthly. Pre-treatment hemoglobin (Hb) ranged from
6.5 to 8.5 gm/dl (mean 7.4 gm/dl), absolute neutrophil
count (ANC) ranged from 180 to 790/cu mm (mean 850/cu
mm) and platelet count ranged from 3000 to 25000/cu
mm (mean 16000/cu mm). LFTs, creatinine and blood pressure
were within normal range.
The
entire group of 19 people was started on two teaspoons
of BH-5 at a 5:1 concentrate powder twice daily, orally.
All were transfusion dependent and did not response
to the most standard treatment for AA: Cyclosporine.
Results:
After one month of using BH-5 herbal therapy: ANC improved
in all 19 people (mean 2400/cu mm), Hb improved in all
19 people (mean 8.6 gm/dl), and platelets showed improvement
in all 19 people (mean 70000/cu mm). After three months
of therapy: ANC improved in all 19 people (mean 3600/cu
mm), Hb improved in all 19 people (mean 9.8 gm/dl),
and platelets improved in all 19 people (mean 96000/cu
mm). 14 people remained in remission after the discontinuation
of the BH-5 therapy for 12 months. 5 people experienced
normal blood counts with the continual use of BH-5 therapy
for more than 12 months. Overall, treatment was well
tolerated with no significant side effects. The quality
of life and kidney functions have been improved remarkably.
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