Molecular Model Development To Explain
Clinical Efficacy of Cell-Saver

Dr. Ba Hoang, M.D., Ph.D., Oncologist, received his training in St.Petersburg, with medical specialties in oncology, immunology and pediatrics. Dr. Ba is also a master herbalist, familiar with Vietnamese, Chinese and Ayurvedic systems. He is clearly one of the best educated physicians I have known. Also, he has a clinical wisdom, which has become legendary, during his short stay in the U.S.

Dr. Ba has had success in treating lung, liver, breast and prostate cancer that far exceeds any reported in the scientific literature. I have talked with a number of patients to confirm some of his reports. Other patients included close friends, colleagues, and relatives of colleagues. In these cases, I have seen reversal of kidney carcinoma, advanced lung cancer, prostate cancer of long standing, and a patient with stage IV breast cancer with bone metastasis who was told by her oncologist that it was time to move to a hospice.

Dr. Ba had indicated to me in relation to my good friend with kidney carcinoma, that he felt confident he could help him. This is especially unusual because kidney carcinoma is usually treated by surgery and the belief is that it cannot be effectively treated by chemotherapy. In 45 days he is free of cancer, confirmed by PET scan, and by an experimental cancer antigen reading.

In considering an advanced lung cancer patient, he told my employee, the sister-in-law of the patient, Dr. Voloshko, that he felt strongly that he could help her brother-in-law. Within some 4 to 6 weeks, the patient appears to be fully recovered, except for a small trace that showed up on an x-ray.

The percentage of patients responding to Dr. Ba's rather simple approach is staggeringly high. Dr. Ba has apparently found some underlying principal which may help us to better understand these serious diseases and effectively treat them. A sample number of case histories are attached. Case histories and laboratory data will be made available.

There are some interesting points, which arise from Dr. Ba's clinical work. The obvious clinical response to his formulations indicates that these preparations have very potent anti-cancer activity without traditional cytotoxic effects, and they also have remarkably fast-acting anti-pain activity without morphine and related analgesics. The pain relief effects occur within days. The preparations are not damaging in any way, are not addictive, nor are they particularly expensive.

Dr. Ba believes these agents include membrane-calming agents. These agents have been clinically effective for asthma, inflammatory bowel diseases, insomnia, seizures, hyperactivity, and chronic pain. He believes that they may stabilize and normalize mineral transport across the plasma cell membranes. Presently we are reviewing data on Voltage Gated Sodium Channels (VGSC) of which Djamoz's work appears to be most prominent. Djamoz finds, consistent with our belief, that the VGSCs appear to be activated in aggressive metastasizing cells. We will comment on another of the published materials on VGSC. The precise role of ion channels in carcinogenesis and tumor progression is poorly understood. In breast cancer, the role of ionic channels has been known since the work of Marino, et. al. in 1994. Marino, A., Illev, I, Schwalke, M. Gonzalez. The association between membrane potential and breast cancer. Tumor Biol. 15: 82-89 1994

Since this pioneering work, the role of ion channels and breast cancer cell lines has been focused mainly on potassium channels. At least four types of potassium channels were shown to exist in the MCF-7 cell line, which is the most extensive cell line. These channels are involved mainly in G1/s transition since their inhibition induced an accumulation of cells in Phase G1 of the cell cycle. See attached reference sheet, and include references 2-8 without the numbers.

In Dr.Ba's view, the hyperactivity and increased number of VGSC could be an comDensatory and surviving mechanism of the cells toward the general energy metabolism problem that caused inflammation, pains and cancers. However, uncontrol hyperativity of VGSC could lead to more metabolism and cell cycle abnormalities, which lead to malignancy and metastasis.

By: Stephen A. Levine, PhD
President
Tel: (415) 925 1751
1-800-5459960